The Center for Dynamical Biomarkers (DBIOM) at Beth Israel Deaconess Medical Center, a major teaching hospital of Harvard Medical School, is focusing on fundamental theory and novel computational algorithms for characterizing physiological states in terms of their dynamical properties. These Dynamical Biomarkers may provide more sensitive and accurate assessments of physiological states than conventional biomarkers.  

 

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Recent Publications

Usefulness of heart rhythm complexity in heart failure detection and diagnosis
CK Peng
Distinct Insular Functional Connectivity Changes Related to Mood and Fatigue Improvements in Major Depressive Disorder Following Tai Chi Training
Yan Ma
Alteration of Power Law Scaling of Spontaneous Brain Activity in Schizophrenia
Albert C Yang
Attributable risk of all-cause mortality in hypertensive adults based on disease risk prediction model
Andrew C Ahn
Heart Rhythm Complexity Predicts Long‐Term Cardiovascular Outcomes in Peritoneal Dialysis Patients
CK Peng
Decomposed Temporal Complexity Analysis of Neural Oscillations and Machine Learning Applied to Alzheimer’s Disease Diagnosis
Albert C Yang
Phenotyping Neuropsychiatric Symptoms Profiles of Alzheimer's Disease Using Cluster Analysis on EEG Power
Albert C Yang, CK Peng
Advances in Multi-Scale Analysis of Brain Complexity
Albert C Yang
Large-Scale Structural Covariance Networks Predict Age in Middle-to-Late Adulthood
Albert C Yang
Age-related changes in the association of resting-state fMRI signal variability and global functional connectivity in non-demented healthy people
Albert C Yang, CK Peng
Measuring time series based on multiscale dispersion Lempel–Ziv complexity and dispersion entropy plane
CK Peng
Multiscale cumulative residual distribution entropy and its applications on heart rate time series
CK Peng, Albert C Yang
Discrimination of Severity of Alzheimer’s Disease with Multiscale Entropy Analysis of EEG Dynamics
Albert C Yang
Sleep heart rate variability assists the automatic prediction of long-term cardiovascular outcomes
Yan Ma
Abnormal topology of brain functional networks in unipolar depression and bipolar disorder using optimal graph thresholding
Albert Yang
Analysis of economic growth fluctuations based on EEMD and causal decomposition
Albert C Yang, CK Peng