The Center for Dynamical Biomarkers (DBIOM) at Beth Israel Deaconess Medical Center, a major teaching hospital of Harvard Medical School, is focusing on fundamental theory and novel computational algorithms for characterizing physiological states in terms of their dynamical properties. These Dynamical Biomarkers may provide more sensitive and accurate assessments of physiological states than conventional biomarkers.  



  • Dynamical Biomarkers Group, led by Prof. Peng and in collaboration with HTC, made it to the final round in the $10 million Qualcomm Tricorder XPRIZE competition. The results were announced on April 12th, 2017. We were proud to accept the runner-up award and look forward to continuing the development of our Tricorder. Please click here for more information.
  • DBIOM has received a generous donation from Ovation Health Institute to support our TCM research and training program.
  • DBIOM has received a generous donation from Delta Electronics Foundation to support our Dynamical Biomarkers Traineeship Program.
  • DBIOM has received a generous donation from World Health, Inc. to support our research and education program.
  • Chaos: An Interdisciplinary Journal of Nonlinear Science is celebrating 25 years of its publication. Prof. Peng's article on Detrended Fluctuation Analysis (DFA) Chaos 5, 82 (1995) was selected in 25 Articles for 25 Years.


Recent Publications

Effects of slow and regular breathing exercise on cardiopulmonary coupling and blood pressure
CK Peng
  • Zhang, Z., Wang, B., Wu, H., Chai, X., Wang, W., & Peng, C. K. (2017). ...
Dynamic Cerebral Autoregulation Assessment Using Extracranial Internal Carotid Artery Doppler Ultrasonography
CK Peng
  • Chi, N. F., Ku, H. L., Wang, C. Y., Liu, Y., Chan, L., Lin, Y. C., ... & Hu, C. J. (2017). ...
Frontal electroencephalogram analysis with ensemble empirical mode decomposition during the induction of general anesthesia
CK Peng
  • Tsai, F. F., Hu, X., Lin, Y. S., Peng, C. K., & Fan, S. Z. (2016). ...
Cardiac autonomic alteration and metabolic syndrome: an ambulatory ECG-based study in a general population
Yan Ma
  • Ma, Y., Tseng, P. H., Ahn, A., Wu, M. S., Ho, Y. L., Chen, M. F., & Peng, C. K. (2017). ...
Ambulatory Blood Pressure Monitoring in Chinese Obstructive Sleep Apnea Patients
Yan Ma
  • Ma, Y., Sun, S., Peng, C. K., Fang, Y., & Thomas, R. J. (2017). ...
A Higher Proportion of Metabolic Syndrome in Chinese Subjects with Sleep-Disordered Breathing: A Case-Control Study Based on Electrocardiogram-Derived Sleep Analysis
CK Peng
  • Tseng, P. H., Lee, P. L., Hsu, W. C., Ma, Y., Lee, Y. C., Chiu, H. M., ... & Peng, C. K. (2017). ...
Reference Values of Heart Rate Variability
CK Peng
  • Bauer, A., Camm, A. J., Cerutti, S., Guzik, P., Huikuri, H., Lombardi, F., ... & Schmidt, G. (2016). ...
Serial heart rhythm complexity changes in patients with anterior wall ST segment elevation myocardial infarction
CK Peng
  • Chiu, H. C., Ma, H. P., Lin, C., Lo, M. T., Lin, L. Y., Wu, C. K., ... & Liu, L. Y. D. (2017). ...
Nonlinear dynamical analysis of sleep electroencephalography using fractal and entropy approaches
Albert C Yang
  • Ma, Y., Shi, W., Peng, C. K., & Yang, A. C. (2017). ...