The Center for Dynamical Biomarkers (DBIOM) at Beth Israel Deaconess Medical Center, a major teaching hospital of Harvard Medical School, is focusing on fundamental theory and novel computational algorithms for characterizing physiological states in terms of their dynamical properties. These Dynamical Biomarkers may provide more sensitive and accurate assessments of physiological states than conventional biomarkers.  

 

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Recent Publications

Dynamic Cerebral Autoregulation Is an Independent Functional Outcome Predictor of Mild Acute Ischemic Stroke
CK Peng
  • Chi, N. F., Hu, H. H., Wang, C. Y., Chan, L., Peng, C. K., Novak, V., & Hu, C. J. (2018). ...
Multiscale joint permutation entropy for complex time series
  • Yin, Y., Shang, P., Ahn, A. C., & Peng, C. K. (2019). ...
Complexity of Wake Electroencephalography Correlates With Slow Wave Activity After Sleep Onset
Yan Ma, CK Peng, Albert C Yang
  • Hou, F., Yu, Z., Peng, C. K., Yang, A., Wu, C., & Ma, Y. (2018). ...
Symbolic dynamics of electroencephalography is associated with the sleep depth and overall sleep quality in healthy adults
Yan Ma, CK Peng, Albert C Yang, Andrew C Ahn
  • Ma, Y., Hou, F., Yang, A. C., Ahn, A. C., Fan, L., & Peng, C. K. (2019). ...
Measuring Brain Complexity During Neural Motor Resonance. 
Albert C Yang
  • Hager, B. M., Yang, A. C., & Gutsell, J. (2018). ...
The association between heart rhythm complexity and the severity of abdominal aorta calcification in peritoneal dialysis patients
CK Peng
  • Tsai, C. H., Lin, C., Ho, Y. H., Lo, M. T., Liu, L. Y. D., Lin, C. T., ... & Lin, Y. H. (2018). ...
Prediction of atrial fibrillation recurrence before catheter ablation using an adaptive nonlinear and non-stationary surface ECG analysis
CK Peng
  • Cui, X., Chang, H. C., Lin, L. Y., Yu, C. C., Hsieh, W. H., Li, W., ... & Lo, M. T. (2019). ...
Characterizing time series by extended complexity-entropy curves based on Tsallis, Rényi, and power spectral entropy. 
Yan Ma
  • Mao, X., Shang, P., Wang, J., & Ma, Y. (2018). ...
Causal decomposition in the mutual causation system
Albert C Yang, CK Peng
  • Yang, A. C., Peng, C. K., & Huang, N. E. (2018). ...