The Center for Dynamical Biomarkers (DBIOM) at Beth Israel Deaconess Medical Center, a major teaching hospital of Harvard Medical School, is focusing on fundamental theory and novel computational algorithms for characterizing physiological states in terms of their dynamical properties.  These Dynamical Biomarkers may provide more sensitive and accurate assessments of physiological states than conventional biomarkers.  


In addition to research activities, Professor C.-K. Peng, Director of DBIOM, is leading a team of physicians, scientists and engineers to compete in the $10 million Qualcomm Tricorder XPRIZE competition.  The goal of this XPRIZE is to develop a light-weight portable system (under 5 lb) for consumer use which can diagnose 12 medical conditions and continuously monitor 5 vital signs with high accuracy.  Our team is excited that we are one of the only two teams advanced to the final round.  The result of this international competition will be announced by April 2017.


  • Dynamical Biomarkers Group, led by Prof. Peng and sponsored by HTC, is one of the final 2 teams in the $10 million Qualcomm Tricorder XPRIZE competition, click here for more information.
  • DBIOM has received a generous donation from Ovation Health Institute to support our TCM research and training program.
  • DBIOM has received a generous donation from Delta Electronics Foundation to support our Dynamical Biomarkers Traineeship Program.
  • DBIOM has received a generous donation from World Health, Inc. to support our research and education program.
  • Chaos: An Interdisciplinary Journal of Nonlinear Science is celebrating 25 years of its publication. Prof. Peng's article on Detrended Fluctuation Analysis (DFA) Chaos 5, 82 (1995) was selected in 25 Articles for 25 Years.


Recent Publications

Neural complexity as a potential translational biomarker for psychosis
Albert C Yang
A comparison study on stages of sleep: Quantifying multiscale complexity using higher moments on coarse-graining
Yan Ma
Publication Trends in Acupuncture Research: A 20-Year Bibliometric Analysis Based on PubMed
Yan Ma
Measuring information-based energy and temperature of literary texts
CK Peng
Sparse representation-based ECG signal enhancement and QRS detection
Andrew C Ahn
The Effects of Tai Chi on Sleep Quality in Chinese American Patients With Major Depressive Disorder: A Pilot Study
Yan Ma
Resting-state EEG power and coherence vary between migraine phases
Albert C Yang
Personality Development since Childhood Associated with Adult Chronic Insomnia: A Study by Wang’s Memory-Tracing Personality Development Inventory (WMPI)
Yan Ma
Heart rate variability in mind-body interventions
Yan Ma